The effect of moderate-intensity acute aerobic exercise duration on the percentage of circulating CD31+ cells in lymphocyte population

  • Mariani Santosa Department of Physiology, Faculty of Medicine, Universitas Indonesia, Jakarta
  • Ermita I.I. Ilyas Department of Physiology, Faculty of Medicine, Universitas Indonesia, Jakarta
  • Radiana D. Antarianto Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta
DOI: https://doi.org/10.13181/mji.v25i1.1277
Keywords: CD31 peripheral blood mononuclear cells, circulating endothelial progenitor cells, endothelial regeneration, exercise
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Abstract

Background: The increasing number of circulating CD31+ endothelial progenitor cells is one of the important factors for maintaining vascular homeostasis. Exercise will effectively increase the number of circulating CD31+ endothelial progenitor cells. This study aims to determine the effect of moderate-intensity acute aerobic exercise duration on the percentage of circulating CD31+ cells in untrained healthy young adult subjects.

Methods: This study was an experimental study. Untrained healthy volunteers (n=20) performed ergocycle at moderate-intensity (64–74% maximum heart rate) for 10 minutes or 30 minutes. Immediately before and 10 minutes after exercise, venous blood samples were drawn. The percentage of CD31+ cells in peripheral blood was analyzed using flow cytometry. Data was statistically analyzed using student t-test.

Results: There were no significant differences in the mean percentage of circulating CD31+ cells before and after exercise for 10 minutes and 30 minutes (p>0.05). However, there was a different trend in the percentage of circulating CD31+ cells after exercise for 10 minutes and 30 minutes. In the 10 minutes duration, 50% of subjects showed increase. Whereas in the 30 minutes duration, 80% of subjects showed increase.

Conclusion: The percentage of circulating CD31+ cells before and after exercise for 10 minutes was not different compared to 30 minutes. However, data analysis shows that majority of subjects (80%) had increased in the percentage of circulating CD31+ cells after 30 minutes exercise.

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Published
2016-04-15
How to Cite
1.
Santosa M, Ilyas EI, Antarianto RD. The effect of moderate-intensity acute aerobic exercise duration on the percentage of circulating CD31<sup>+</sup&gt; cells in lymphocyte population. Med J Indones [Internet]. 2016Apr.15 [cited 2024Apr.25];25(1):51-6. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/1277
Issue
Vol. 25 No. 1 (2016): March
Section
Clinical Research

Copyright (c) 2016 Mariani Santosa, Ermita I.I. Ilyas, Radiana D. Antarianto

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