Primary malignant giant cell tumor of the patella: report of a rare case

  • Achmad F. Kamal Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Errol U. Hutagalung Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Saukani Gumay Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Yogi Prabowo Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Yanuarso Yanuarso Department of Orthopaedic and Traumatology, Gatot Subroto Central Army Hospital, Jakarta, Indonesia
DOI: https://doi.org/10.13181/mji.v22i4.607
Keywords: Limb sparing surgery, primary malignant GCT, total patellectomy
Abstract viewed: 1470 times
PDF downloaded: 1095 times

Abstract

Primary malignant giant cell tumor (GCT) at the patella bone is a very rare case. It is a high-grade sarcoma characterized by a lesion in which there are areas of synchronous high-grade sarcomatous next to areas of benign GCT. A limb sparing approach is applicable to virtually any bone lesion, whether low grade or high grade. We report a case with primary malignant GCT at the patella, from diagnostic to detailed limb sparing surgery procedure. Fifteen months after surgery, the patient had a good functional outcome without local recurrence and distant metastasis. (Med J Indones. 2013;22:238-42. doi: 10.13181/mji.v22i4.607)

References

  1. Murphey MD, Nomikos GC, Flemming DJ, Gannon FH, Temple HT, Kransdorf MJ. From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic correlation. Radiographics. 2001;21(5):1283-309. http://dx.doi.org/10.1148/radiographics.21.5.g01se251283

  2. Unni KK. Giant cell tumor (osteoclastoma). In: Dahlin's bone tumors - general aspects and data on 11,087 cases. 5th edition. Philadelphia: Lippincott Williams & Wilkins; 1996.p.263-82.

  3. Unni KK, Inwards CY, Bridge JA, Kindblom L-G, Wold LE. AFIP atlas of tumour pathology series 4: tumours of the bones and joints. Washington: AFIP-ARP; 2005.

  4. Unni KK. Malignancy in giant cell tumor of bone. In: Dahlin's bone tumors - general aspects and data on 11,087 cases. 5th edition. Philadelphia: Lippincott Williams & Wilkins; 1996.p.285-9.

  5. Bullough PG, Bansal M. Malignancy in giant cell tumour. In: Fletcher CDM, Unni KK, Mertens F, editors. World health organization classification of tumours, pathology, and genetics of tumours of soft tissue and bone. Geneva: IARC Press; 2002.p.313.

  6. Sung HW, Kuo DP, Shu WP, Chai YB, Liu CC, Li SM. Giant-cell tumor of bone: analysis of two hundred and eight cases in Chinese patients. J Bone Joint Surg Am. 1982;64(5):755-61.

  7. Reddy CRRM, Rao PS, Rajakumari K. Giant-cell tumors of bone in south India. J Bone Joint Surg Am. 1974;56(3):617-9.

  8. Manaster BJ, Doyle AJ. Giant cell tumors of bone. Radiol Clin North Am. 1993;31(2):299-323.

  9. Larsson SE, Lorentzon R, Boquist L. Giant-cell tumor of bone. A demographic, clinical, and histopathological study of all cases recorded in the Swedish Cancer Registry for the years 1958 through 1968. J Bone Joint Surg Am. 1975;57(2):167-73.

  10. Hong SW, Choi HY. Malignant giant cell tumor of the skull. J Korean Neurosurg Soc. 2004;36(4):324-7.

  11. Greenspan A. Orthopedic imaging: a practical approach. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2004.p.136-54.

  12. Armen KK, Nolan SK. Lower extremity reconstruction. In: Charles HT, editor. Grabb and Smith's plastic surgery. 6th ed. Washington: Lippincott Williams & Wilkins; 2007.p.1031-49.

  13. Domovitov SV, Healey JH. Primary malignant giant-cell tumor of bone has high survival rate. Ann Surg Oncol. 2010;17(3):694-701. http://dx.doi.org/10.1245/s10434-009-0803-z

Published
2013-12-13
How to Cite
1.
Kamal AF, Hutagalung EU, Gumay S, Prabowo Y, Yanuarso Y. Primary malignant giant cell tumor of the patella: report of a rare case. Med J Indones [Internet]. 2013Dec.13 [cited 2024Apr.19];22(4):238-42. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/607
Issue
Vol. 22 No. 4 (2013): November
Section
Case Report/Series

Copyright (c) 2013 Achmad F. Kamal, Errol U. Hutagalung, Saukani Gumay, Yogi Prabowo, Yanuarso Yanuarso

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with Medical Journal of Indonesia agree to the following terms:

  1. Authors retain copyright and grant Medical Journal of Indonesia right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial License that allows others to remix, adapt, build upon the work non-commercially with an acknowledgment of the work’s authorship and initial publication in Medical Journal of Indonesia.
  2. Authors are permitted to copy and redistribute the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Medical Journal of Indonesia.

Most read articles by the same author(s)