TY - JOUR AU - Henky Henky AU - Yuli Budiningsih AU - Wibisana Widiatmaka PY - 2011/11/01 Y2 - 2024/03/29 TI - The validity of rapid test to detect prostate-specific antigen (PSA) in seminal fluid JF - Medical Journal of Indonesia JA - Med J Indones VL - 20 IS - 4 SE - Clinical Research DO - 10.13181/mji.v20i4.464 UR - http://mji.ui.ac.id/journal/index.php/mji/article/view/464 AB - Background: This study was conducted to determine whether the rapid test device can be used to detect PSA in seminal fluid specifically, for solving sexual assault cases.Methods: A cross sectional study has been conducted. A total of 45 samples were taken consecutively. Semen was diluted in serially up to 1:5.000.000 and male urin up to 1:200 using distilled water, whereas female urin was not diluted. Samples were analyzed using rapid test PSA.Results: The proportion of positive results of PSA in seminal fluid, male urin and female urin respectively was 100%, 6.67%, and 0%. Statistically, these differences are highly significant. The analysis revealed that the PSA rapid test device was 100% sensitive and 96.67% specific to detect seminal fluid. The test also have PPV 93.75%, NPV 100%, LR(+) 33.33, LR(-) 0, and AUC 0.983.Conclusion: PSA Rapid Test is very specific and sensitive to detect PSA in seminal fluid. Therefore, this device is suggested for forensic use in sexual assault cases. (Med J Indones 2011; 20:278-82) ER -