Incidence and associated factors of posterior capsule opacification in pseudophakic patients at Cipto Mangunkusumo Hospital

Authors

  • Sita P. Ayuningtyas Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
  • Tjahjono D. Gondhowiardjo Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta

DOI:

https://doi.org/10.13181/mji.v24i3.1199

Keywords:

incidence, intraocular lens, posterior capsule opacification

Abstract

Background: Posterior capsule opacification (PCO) is the most common postoperative consequence of cataract surgery which may cause visual acuity reduction, yet the incidence in Indonesia has not been reported. The objectives of this study were to evaluate three years cumulative incidence of PCO and factors associated with PCO formation at Cipto Mangunkusumo Hospital, Jakarta.

Methods: This was a retrospective descriptive study on patients with uneventful senile cataract surgery during year 2010. All related data were retrieved from medical records in year 2013, which included patient demographics, type of surgery, intraocular lens (IOL) characteristics (material, optic edge design and diameter). Moreover, time to first PCO diagnosis (month), and best corrected visual acuity (BCVA) pre-operatively, at time PCO was diagnosed and two weeks after Neodymium-doped yttrium aluminum garnet (Nd:YAG) laser were noted (decimal).

Results: A total of 578 eyes (485 patients) were involved in this study. Three years cumulative incidence of the PCO was 8.82% (51 eyes). Phacoemulsification surgery was performed in 496 (85.8%) eyes. The median time to PCO diagnosis was 21 months (range 1 to 34 months), mean of BCVA was 0.50 ± 0.26. Age (<65 and >65 years old) was not associated to PCO. Higher incidence of PCO was found in patients using hydrophilic acrylic IOL (10.7%) than in hydrophobic acrylic (6.2%). After Nd:YAG laser was performed, BCVA was improved to 1.00.

Conclusion: Three years cumulative incidence of PCO was 8.82% and there was no defined factor related to PCO formation, but higher percentage of PCO occured in patients using hydrophilic acrylic IOL than in hydrophobic acrylic.

Downloads

Download data is not yet available.

Author Biographies

Sita P. Ayuningtyas, Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta

Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia,Cipto Mangunkusumo Hospital, Jakarta

Tjahjono D. Gondhowiardjo, Department of Ophthalmology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta

Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta

References

Raj SM, Vasavada AR, Johar SRK, Vasadava VA, Vasavada VA. Post-operative capsular opacification: a review. Int J Biomed Sci. 2007;3(4):237-50.

Fong CS, Mitchell P, Rochtchina E, Cugati S, Hong T, Wang JJ. Three-year incidence and factors associated with posterior capsule opacification after cataract surgery: The Australian prospective cataract surgery and age-related macular degeneration study. Am J Ophthalmol. 2014;157(1):171-9. http://dx.doi.org/10.1016/j.ajo.2013.08.016

Van Bree MC, van den Berg TJ, Zijlmans BL. Posterior capsule opacification severity, assessed with straylight measurement, as main indicator of early visual function deterioration. Ophthalmology. 2013;120(1):20-33. http://dx.doi.org/10.1016/j.ophtha.2012.07.050

Wakamatsu TH, Yamaguchi T, Negishi K, Kaido M, Matsumoto Y, Ishida R, et al. Functional visual acuity after neodymium:YAG laser capsulotomy in patients with posterior capsule opacification and good visual acuity preoperatively. J Cataract Refract Surg. 2011;37(2):258-64. http://dx.doi.org/10.1016/j.jcrs.2010.08.048

Awasthi N, Guo S, Wagner BJ. Posterior capsular opacification: a problem reduced but not yet eradicated. Arch Ophthalmol. 2009;127(4):555-62. http://dx.doi.org/10.1001/archophthalmol.2009.3

Khanzada MA, Jatoi SM, Narsani AK, Dabir SA, Gul S. Is the Nd:YAG laser a safe procedure for posterior capsulotomy? Pak J Ophthalmol. 2008;24(2):73-8.

Anggraini N, Hutauruk J. Insiden dan karakteristik posterior capsule opacification pasca ekstraksi katarak dengan implantasi posterior chamber-intraocular lens: Studi deskriptif. Departemen Ilmu Kesehatan Mata Fakultas Kedokteran Universitas Indonesia. 2005. Indonesian.

Shah SP, Gilbert CE, Razavi H, Turner EL, Lindfield RJ. Preoperative visual acuity among cataract surgery patients and countries' state of development: a global study. Bull World Health Organ. 2011;89(10):749-56. http://dx.doi.org/10.2471/BLT.10.080366

Gollogly HE, Hodge DO, St Sauver JL, Erie JC. Increasing incidence of cataract surgery: population-based study. J Cataract Refract Surg. 2013;39(9):1383-9. http://dx.doi.org/10.1016/j.jcrs.2013.03.027

Bobrow JC, Blecher MH, Glasser DB, Mitchell KB, Rosenberg LF, Reich J, et al. Surgery for cataract. In: Skuta GL, Cantor LB, Weiss JS, editors. Basic and clinical science course: lens and cataract. San Francisco: American Academy of Ophthalmology; 2011. p. 91-160.

Wormstone IM, Wang L, Liu C. Posterior capsule opacification. Experimental Eye Research. 2009;88:257-69. http://dx.doi.org/10.1016/j.exer.2008.10.016

Khan MY, Jan S, Khan MN, Khan S, Kundi N. Visual outcome after Nd:YAG capsulotomy in posterior capsule opacification. Pak J Ophthalmol 2006;22(2).

Khanzada MA, Gul S, Dabir SA, Jatoi SM, Narsani AK. Comparative incidence of posterior capsular opacification in AcrySof and PMMA intraocular lenses. Int J Ophthalmol. 2009;2(2):150-3.

Aslam TM, Devlin H, Dhillon B. Use of Nd:YAG laser capsulotomy. Surv Ophthalmol. 2003;48(6):594-612. http://dx.doi.org/10.1016/j.survophthal.2003.08.002

Lundqvist B, Mönestam E. Ten-year longitudinal visual function and Nd:YAG laser capsulotomy rates in patients less than 65 years at cataract surgery. Am J Ophthalmol. 2010;149(2):238-44. http://dx.doi.org/10.1016/j.ajo.2009.08.029

Moulick CP, Rodrigues CFEA, Shyamsundar LCK. Evaluation of posterior capsular opacification following phacoemulsification, extracapsular and small incision cataract surgery. MJAFI. 2009;65:225-8. http://dx.doi.org/10.1016/s0377-1237(09)80008-7

Linnola RJ, Sund M, Ylönen R, Pihlajaniemi T. Adhesion of soluble fibronectin, laminin, and collagen type IV to intraocular lens materials. J Cataract Refract Surg. 1999;25(11):1486-91. http://dx.doi.org/10.1016/S0886-3350(99)00238-2

Kugelberg M, Wejde G, Jayaram H, H, Zetterström C. Two-year follow-up of posterior capsule opacification after implantation of a hydrophilic or hydrophobic acrylic intraocular lens. Acta Ophthalmol. 2008;86(5):533-6. http://dx.doi.org/10.1111/j.1600-0420.2007.01094.x

Saeed MU, Jafree AJ, Saeed MS, Zia R, Sheikh IM, Heravi M. Intraocular lens and capsule opacification with hydrophilic and hydrophobic acrylic materials. Semin Ophthalmol. 2012;27(1-2):15-8. http://dx.doi.org/10.3109/08820538.2011.588651

Meacock WR, Spalton DJ, Boyce JF, Jose RM. Effect of optic size on posterior capsule opacification: 5.5 mm versus 6.0 mm AcrySof intraocular lenses. J Cataract Refract Surg. 2001;27(8):1194-8. http://dx.doi.org/10.1016/S0886-3350(01)00855-0

Nishi O, Nishi K. Effect of the optic size of a single-piece acrylic intraocular lens on posterior capsule opacification. J Cataract Refract Surg. 2003;29(2):348-53. http://dx.doi.org/10.1016/S0886-3350(02)01530-4

Buehl W, Findl O, Menapace R, Sacu S, Kriechbaum K, Koeppl C, et al. Long-term effect of optic edge design in an acrylic intraocular lens on posterior capsule opacification. J Cataract Refract Surg. 2005;31(5):954-61. http://dx.doi.org/10.1016/j.jcrs.2004.09.053

Kohnen T, Fabian E, Gerl R, Hunold W, , Hütz W, Strobel J, et al. Optic edge as long-term factor for posterior capsule opacification rates. Ophthalmology. 2008;115(8):1308-14. http://dx.doi.org/10.1016/j.ophtha.2008.01.002

Hayashi K, Hayashi H. Posterior capsule opacification in the presence of an intraocular lens with a sharp versus rounded optic edge. Ophthalmology. 2005;112(9):1550-6. http://dx.doi.org/10.1016/j.ophtha.2005.03.024

Downloads

Published

2015-11-09

How to Cite

1.
Ayuningtyas SP, Gondhowiardjo TD. Incidence and associated factors of posterior capsule opacification in pseudophakic patients at Cipto Mangunkusumo Hospital. Med J Indones [Internet]. 2015Nov.9 [cited 2024Nov.5];24(3):176-82. Available from: https://mji.ui.ac.id/journal/index.php/mji/article/view/1199

Issue

Section

Clinical Research
Abstract viewed = 2599 times

Most read articles by the same author(s)