<em>Streptococcus suis</em> meningitis related to processing and consuming raw pork during Balinese tradition, <em>Mebat</em>

IGM Ardika Aryasa; Ni Putu Ayu Widiasari; Ni Made Susilawathi; Ni Nengah Dwi Fatmawati; I Made Oka Adnyana; Anak Agung Raka Sudewi; Ni Made Adi Tarini

doi:10.13181/mji.cr.193249

Authors

IGM Ardika Aryasa Faculty of Medicine, Universitas Udayana, Bali, Indonesia https://orcid.org/0000-0003-0014-439X
Ni Putu Ayu Widiasari Faculty of Medicine, Universitas Udayana, Bali, Indonesia
Ni Made Susilawathi Department of Neurology, Faculty of Medicine, Universitas Udayana/Sanglah General Hospital, Bali, Indonesia
Ni Nengah Dwi Fatmawati Department of Clinical Microbiology, Faculty of Medicine, Universitas Udayana/Sanglah General Hospital, Bali, Indonesia
I Made Oka Adnyana Department of Neurology, Faculty of Medicine, Universitas Udayana/Sanglah General Hospital, Bali, Indonesia
Anak Agung Raka Sudewi Department of Neurology, Faculty of Medicine, Universitas Udayana/Sanglah General Hospital, Bali, Indonesia
Ni Made Adi Tarini Department of Clinical Microbiology, Faculty of Medicine, Universitas Udayana/Sanglah General Hospital, Bali, Indonesia

DOI:

https://doi.org/10.13181/mji.cr.193249

Keywords:

foodborne disease, meningitis, polymerase chain reaction, Streptococcus suis

Abstract

Streptococcus suis is a zoonotic pathogen that can infect humans, especially meningitis. S. suis meningitis has been commonly diagnosed in Bali, which is associated with the consumption of raw pork. We reported case of S. suis meningitis that could have occurred due to the ingestion of undercooked pork during a traditional ceremony, which also involved two more patients with similar symptoms. A 62-year-old male was brought to the emergency unit because of decreased consciousness (Glasgow coma scale 14/15) in the last 8 hours before admission. He also had a headache, high fever, and stiff neck. Examination of cerebrospinal fluid revealed the presence of S. suis infection and was confirmed by polymerase chain reaction. The patient was administered ceftriaxone and showed a clinical improvement on the third day without any hearing problem.

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References

van Samkar A, Brouwer MC, Schultsz C, van der Ende A, van de Beek D. Streptococcus suis meningitis: a systematic review and meta-analysis. PLoS Negl Trop Dis. 2015;9(10):e0004191. https://doi.org/10.1371/journal.pntd.0004191

Ma E, Chung PH, So T, Wong L, Choi KM, Cheung DT, et al. Streptococcus suis infection in Hong Kong: an emerging infectious disease? Epidemiol Infect. 2008;136(12):1691-7. https://doi.org/10.1017/S0950268808000332

Krauss H, Weber A, Appel M, editors. Zoonoses infectious diseases transmissible from animals to humans. 3rd ed. Washington: ASM Press; 2003. p. 239-40. https://doi.org/10.1128/9781555817787

World Health Organization Regional Office for the Western Pacific. Streptococcus suis [Internet]. 2017 [cited 2017 Apr 15]. Available from: http://www.wpro.who.int/mediacentre/factsheets/fs_20050802/en/.

Nghia HD, Tu le TP, Wolbers M, Thai CQ, Hoang NV, Nga TV, et al. Risk factors of Streptococcus suis infection in Vietnam. A case-control study. PLoS One. 2011;6(3):e17604. https://doi.org/10.1371/journal.pone.0017604

Takeuchi D, Kerdsin A, Pienpringam A, Loetthong P, Samerchea S, Luangsuk P, et al. Population-based study of Streptococcus suis infection in humans in Phayao Province in Northern Thailand. PLoS One. 2012;7(2):e31265. https://doi.org/10.1371/journal.pone.0031265

Yu H, Jing H, Chen Z, Zheng H, Zhu X, Wang H, et al. Human Streptococcus suis outbreak, Sichuan, China. Emerg Infect Dis. 2006;12(6):914-20. https://doi.org/10.3201/eid1206.051194

Susilawathi NM, Tarini NM, Fatmawati NN, Mayura PI, Suryapraba AA, Subrata M, et al. Streptococcus suis-associated meningitis, Bali, Indonesia, 2014-2017. Emerg Infect Dis. 2019;25(12):2235-42. https://doi.org/10.3201/eid2512.181709

Okwumabua O, O'Connor M, Shull E. A polymerase chain reaction (PCR) assay specific for Streptococcus suis based on the gene encoding the glutamate dehydrogenase. FEMS Microbiol Lett. 2003;218(1):79-84. https://doi.org/10.1111/j.1574-6968.2003.tb11501.x

Susilawathi NM, Tarini NM, Sudewi AA. Bacterial meningitis Streptoccocus suis with bilateral sensorineural hearing loss. Neurona. 2016;34(1):55-9. Indonesian.

Budiarsa K. Potential of pig farming in contributing to fulfill livestock needs in Bali. National Seminar of Pig Farming, Faculty of Animals Husbandry. Universitas Udayana. 2014. Indonesian.

Bhimraj A. Acute community-acquired bacterial meningitis. In: Garcia Monco JC (ed). CNS infection: a clinical approach. 2nd ed. Switzerland: Springer; 2018. p. 19-30. https://doi.org/10.1007/978-3-319-70296-4_2

Tarini NMA, Setiabudy M, Susilawathi NM, Fatmawati NND, Mayura IPB, Darwinata EA, et al. Misidentification of S. suis as a zoonotic agent. Maced J Med Sci. 2019;7(14):2309-12. https://doi.org/10.3889/oamjms.2019.619

Wertheim HF, Nghia HD, Taylor W, Schultsz C. Streptococcus suis: an emerging human pathogen. Clin Infect Dis. 2009;48:617-25. https://doi.org/10.1086/596763

Tan JH, Yeh BI, Seet CS. Deafness due to haemorrhagic labyrinthitis and a review of relapses in Streptococcus suis meningitis. Singapore Med J. 2010;51(2):e30-3.