The impact of sleep quality and duration on leptin, appetite, and obesity indices in adults

  • Harry Freitag Luglio Muhammad Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia
  • Satwika Arya Pratama Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia https://orcid.org/0000-0002-8684-257X
  • Dian Caturini Sulistyoningrum Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia
  • Maya Nurfitriani Hartono Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia
  • Emy Huriyati Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia
  • Yi Yi Lee Division of Nutrition and Dietetics, International Medical University, Kuala Lumpur, Malaysia
  • Wan Abdul Manan Wan Muda Department of Nutrition Science, Faculty of Health Science, Universitas Alma Ata, Yogyakarta, Indonesia https://orcid.org/0000-0003-4241-3869
Keywords: appetite, leptin, obesity, sleep quality, sleep duration
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Abstract

BACKGROUND Poor sleep duration and quality were previously reported to increase the risk of obesity. This study was aimed to evaluate the impact of sleep quality and duration on leptin, appetite, and adiposity in Indonesian adults.

METHODS This cross-sectional study recruited adults in Yogyakarta, Indonesia, in 2016. Sleep quality was assessed using the Pittsburgh sleep quality index, appetite was evaluated using the community nutrition appetite questionnaire, and dietary intake was assessed by interviews using the semi-quantitative food frequency questionnaire. Sleep duration was also asked. Obesity indices were measured using the body mass index (BMI), waist-hip circumference, and percentage of body fat. Leptin was analyzed using the enzyme-linked immunosorbent assay. A Spearman analysis was done to evaluate the correlation between sleep quality, sleep duration, anthropometric measures, dietary intake, appetite, and leptin.

RESULTS 244 adults participated in this study. This study showed that lower sleep quality and duration was significantly correlated with higher body weight (r = 0.129, p = 0.043 and r = −0.228, p<0.001), BMI (r = 0.176, p = 0.006 and r = −0.202, p = 0.001), and waist circumference (r = 0.179, p = 0.005 and r = −0.254, p<0.001). There was a correlation between poor sleep quality and higher leptin concentration (r = 0.186, p = 0.004). Sleep quality and duration were not associated with appetite (r = 0.109, p = 0.109 and r = −0.043, p = 0.500).

CONCLUSIONS This study found that lower sleep quality was correlated with higher BMI, higher leptin concentration, but not appetite.

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Published
2020-12-30
How to Cite
1.
Muhammad HFL, Pratama SA, Sulistyoningrum DC, Hartono MN, Huriyati E, Lee YY, Muda WAMW. The impact of sleep quality and duration on leptin, appetite, and obesity indices in adults. Med J Indones [Internet]. 2020Dec.30 [cited 2021Oct.26];29(4):417-21. Available from: https://mji.ui.ac.id/journal/index.php/mji/article/view/3707
Section
Community Research