Assessing Endothelial Function in Normotensive Overweight Adolescent Using Dundee Step Test
Aim Normotensive overweight adolescents may have endothelial dysfunction which is not clinically detected in a routine clinical examination. The purpose of this study was to detect endothelial dysfunction in normotensive overweight using Dundee step test.
Methods Sixty two subjects consist of 31 normoweight and 31 overweight group participated in this study. Blood pressure measurement was taken at rest and after 3 minutes Dundee step test. Hyper-responder was defined if systolic blood pressure reach 180 mmHg or more after 3 minutes exercise.
Results Mann-Whitney test showed that overweight subjects had significantly higher resting systolic blood pressure, post exercise blood pressure anf magnitude of SBP change (Δ SBP) compared to control subjects (116.5 vs 112.8; 163.8 vs 142.7 vs; and 47.3 vs 29.9; P<0.05). Twenty six percent of overweight was diagnosed as hyper-responder.
Conclusion There was significant association between overweight and ExSBP indicating endothelial dysfunction in normotensive overweight adolescents. (Med J Indones 2010; 19:52-6)
Keywords: adolescent, Dundee step test, endothelial dysfunction, overweight, systolic blood pressure
Copyright (c) 2010 Nawanto A. Prastowo, Rika Haryono, Peggy Lucida, Stella K. Indra
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with Medical Journal of Indonesia agree to the following terms:
- Authors retain copyright and grant Medical Journal of Indonesia right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial License that allows others to remix, adapt, build upon the work non-commercially with an acknowledgment of the work’s authorship and initial publication in Medical Journal of Indonesia.
- Authors are permitted to copy and redistribute the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Medical Journal of Indonesia.