Non-psychogenic polydipsia in 45-year-old man with primary hyperparathyroidism and recurrent bilateral nephrolithiasis

  • Rahmat Cahyanur Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
  • Johannes Sarwono Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
  • Linda Armelia Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
  • Maruhum B.H. Marbun Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
  • Pradana Soewondo Division of Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
Keywords: Hyponatremia, non-psychogenic polydipsia, primary hyperparathyroidism
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Abstract

Non-psychogenic polydipsia with hyponatremia is a rare clinical presentation. Primary hyperparathyroidism is a disorder of calcium, phosphate, and bone metabolism caused by increased level of parathyroid hormone (PTH). It is estimated the incidence of primary hyperparathyroidism are 21.6 per 100,000 person a year. This case report describe a 45-year-old man presented with non-psychogenic polydipsia. This patient drank a lot of water out of the fear of recurrent kidney stones. He had history of recurrent nephrolithiasis with hypercalcemia. We investigate further the cause of hypercalcemia and we diagnosed primary hyperparathryoidism as the cause. (Med J Indones. 2012;21:230-4)

References

  1. Weiss GJ. Non-psychogenic polydipsia with hyponatremia. Int J Nephrol. 2005;2(1)

  2. Potts JT. Diseases of parathyroid gland and other hyper- and hypocalcemic disorders. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J, editors. 17th ed. New York: McGraw Hills; 2008. p. 2377-96.

  3. Wermers R, Khosla S, Atkinson E, Achenbach S, Oberg A, Grant C, et al. Incidence of primary hyperparathyroidism in Rochester, Minnesota, 1993-2001: an update on the changing epidemiology of the disease. J Bone Miner Res. 2006;21:171-7. https://doi.org/10.1359/JBMR.050910

  4. Fuleihan GE-H, Silverberg SJ. Clinical manifestations of prymary hyperparathyroidism [Internet]. 2009. Available from: http://www.uptodate.com/contents/clinical-manifestations-of-primary-hyperparathyroidism.

  5. Preminger GM, Curhan GC. The first kidney stone and asymptomatic nephrolithiasis in adults [Internet]. 2009. Available from: http://www.uptodate.com/contents/the-first-kidney-stone-and-asymptomatic-nephrolithiasis-in-adults.

  6. Worcester EM, Coe FL. Nephrolithiasis. Prim Care. 2008;35:369-91. https://doi.org/10.1016/j.pop.2008.01.005

  7. Marcocci C, Cetani F. Clinical practice. Primary hyperparathyroidism. N Engl J Med. 2011;365:2389-97. https://doi.org/10.1056/NEJMcp1106636

  8. Parathyroid gland & calcium & phosphate regulation. In: Molina PE, editor. Endocrine physiology. New York: McGraw Hills; 2010.

  9. Bilezikian JP. Primary hyperparathyroidism. New York [cited 2011 Dec 26]; Available from: http://www.endotext.org/parathyroid/parathyroid5/parathyroidframe5 .htm.

  10. Curhan GC. Prevention of recurrent calcium stones in adults [Internet]. 2009. Available from: http://www.uptodate.com/contents/prevention-of-recurrent-calcium-stones-in-adults.

  11. Perrier ND, Dickson PV. Parathyroid exploration for primary hyperparathyroidism [Internet]. 2011. Available from: http://www.uptodate.com/contents/parathyroid-exploration-for-primary-hyperparathyroidism.

Published
2012-11-01
How to Cite
1.
Cahyanur R, Sarwono J, Armelia L, Marbun MB, Soewondo P. Non-psychogenic polydipsia in 45-year-old man with primary hyperparathyroidism and recurrent bilateral nephrolithiasis. Med J Indones [Internet]. 2012Nov.1 [cited 2021Oct.23];21(4):230-4. Available from: https://mji.ui.ac.id/journal/index.php/mji/article/view/506
Section
Case Report/Series