Stevens Johnson Syndrome in a patient with systemic lupus erythematosus on tuberculostatic treatment
DOI:
https://doi.org/10.13181/mji.v21i4.507Keywords:
Stevens Johnson Syndrome, systemic lupus erythematosusAbstract
A 22-year-old woman was admitted to the hospital because of 5-days history of redness and itch on her face. Additional complains were swelling on her feet, sore throat, and cough. Patient was on treatment for systemic lupus erythematosus and pulmonary tuberculosis (since 12 days). On physical examination, patient was alert, stable hemodynamic, anasarca edema, multiple purpuric macules lesion spread on her body, conjunctivitis of both eyes, multiple oral ulcers, erythema on genital mucosa. Laboratory results were anemia, leucopenia, hypoalbuminemia, proteinuria. We suspected this patient as Stevens Johnson syndrome due to tuberculostatic drugs. During treatment, we stopped the tuberculostatic drugs, and gave her parenteral methylprednisolone, with other supportive treatments. The patient was discharge after improvement of clinical condition and capable of self mobilization. (Med J Indones. 2012;21:235-9)
Downloads
References
Hahn BH. Systemic lupus erythemathosus. In: Longo DL, Kasper DL, Jameson JL, Fauci AS, Hauser SL, Loscalzo J, editors. Harrison's principal of internal medicine. 18th ed. USA: The McGraw-Hill Companies, Inc.; 2012. p. 2724-35.
Tutuncu ZN, Kalunian KC. The definition and classification of systemic lupus erythematosus. In: Wallace DJ, Hahn BH, editors. Dubois' lupus erythematosus. 7th ed. USA: Lippincott Williams & Wilkins; 2007. p. 16-20.
Hahn BH. Systemic lupus erythematosus. In: Fauci AS, Langford CA, editors. Harrison's rheumatology. 2nd ed. USA: The McGraw-Hill Companies, Inc.; 2010. p. 66-81.
Pisetsky DS. Systemic lupus erythematosus: B. Epidemiology, pathology, and pathogenesis. In: Klippel JH, Stone JH, Crofford LJ, White PH, editors. Primer on the rheumatic disease. 13th ed. USA: Springer Science+Bussiness Media, LLC; 2008. p. 319-26.
Buyon JP. Systemic lupus erythematosus: A. Clinical and laboratory features. In: Klippel JH, Stone JH, Crofford LJ, White PH, editors. Primer on the rheumatic disease. 13th ed. USA: Springer Science+Bussiness Media, LLC; 2008. p. 303-18. https://doi.org/10.1007/978-0-387-68566-3_15
Ruiz-Irastorza G, Olivares N, Ruiz-Arruza I, Martinez-Berriotxoa A, Egurbide MV, Aguirre C. Predictors of major infections in systemic lupus erythematosus. Arthritis Res Ther. 2009;11(4):1-8. https://doi.org/10.1186/ar2764
Schulz SW, Derk CT. The gastrointestinal manifestations of systemic lupus erythematosus: a survey of the literature. The Open Autoimmunity Journal. 2009;1:10-26. https://doi.org/10.2174/1876894600901010010
Fritsch PO, Maldonado RR. Erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editors. Fitzpatrick's dermatology in general medicine. 6th ed. USA: The McGraw-Hill Companies, Inc.; 2003.
Djuanda A, Hamzah M. Sindrom Stevens-Johnson. In: Djuanda A, Hamzah M, Aisah S, editors. Ilmu penyakit kulit dan kelamin. 4th ed. Jakarta: Balai Penerbit FKUI; 2005. p.163-5. Indonesian.
Bertsias G, Loannidis JPA, Boletis J, Bombardieri S, Cervera R, Dostal C, et al. EULAR recommendations for the management of systemic lupus erythematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies including Therapeutics. Ann Rheum Dis. 2008;67:195-205. https://doi.org/10.1136/ard.2007.070367
Manzi S, Kao AH. Systemic lupus erythematosus: C. Treatment and assessment. In: Klippel JH, Stone JH, Crofford LJ, White PH, editors. Primer on the rheumatic disease. 13th ed. USA: Springer Science+Bussiness Media, LLC; 2008. p. 327-38.
Tyagi S, Kumar S, Kumar A, Singla M, Singh A. Stevens-Johnson syndrome- a life threatening skin disorder: a review. J Chem Pharm Res. 2010;2(2):618-26.
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with Medical Journal of Indonesia agree to the following terms:
- Authors retain copyright and grant Medical Journal of Indonesia right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial License that allows others to remix, adapt, build upon the work non-commercially with an acknowledgment of the work’s authorship and initial publication in Medical Journal of Indonesia.
- Authors are permitted to copy and redistribute the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Medical Journal of Indonesia.
