Primary rectal melanoma - a case report

Somak Das, Tuhin S. Mandal, Souvik Paul, Purnendu Datta, Aloke K. Sinhababu



DOI: https://doi.org/10.13181/mji.v23i4.1006

Abstract


The most common site for malignant melanoma is skin, then eye and third is anorectal region. Primary anorectal malignant melanoma is still very uncommon. It is usually very aggressive and presents with altered bowel habit and rectal bleeding. Proctoscopy shows non-pigmented or lightly pigmented polypoid lesion. Histopathology is confirmatory. Early radical excision is mandatory. A 56 year-old female was presented with malignant melanoma of the lower third of rectum. We report this case for its rarity.


Keywords


malignant melanoma; rectum; radical excision

Full Text:

PDF

References


  1. Wanebo HJ, Woodruff JM, Farr GH, Quan SH. Anorectal melanoma. Cancer. 1981 Apr 1;47(7):1891-900. http://dx.doi.org/10.1002/1097-0142(19810401)47:7<1891::AID-CNCR2820470730>3.0.CO;2-K
  2. Moore R. Recurrent melanosis of the rectum, after previous removal from the verge of the anus, in a man aged sixty-five. Lancet. 1857;69(1751):290. http://dx.doi.org/10.1016/S0140-6736(02)20230-5
  3. Roumen RM. Anorectal melanoma in The Netherlands: a report of 63 patients. Eur J Surg Oncol. 1996 Dec;22(6):598-601. http://dx.doi.org/10.1016/S0748-7983(96)92346-X
  4. Helmke BM, Otto HF. Anorectal melanoma. A rare and highly malignant tumor entity of the anal canal. Pathologe. 2004;25(3):171-7. German http://dx.doi.org/10.1007/s00292-003-0640-y
  5. Goldman S1, Glimelius B, Påhlman L. Anorectal malignant melanoma in Sweden. Dis Colon Rectum. 1990;33(10):874-7. http://dx.doi.org/10.1007/BF02051925
  6. Weinstock MA. Epidemiology and prognosis of anorectal melanoma. Gastroenterology. 1993;104(1):174-8.
  7. Chang AE, Karnell LH, Menck HR. The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer. 1998;83(8):1664-78. http://dx.doi.org/10.1002/(SICI)1097-0142(19981015)83:8<1664::AID-CNCR23>3.0.CO;2-G
  8. Podnos YD, Tsai NC, Smith D, Ellenhorn JD. Factors affecting survival in patients with anal melanoma. Am Surg. 2006;72(10):917-20.
  9. Weyandt GH, Eggert AO, Houf M, Raulf F, Bröcker EB, Becker JC. Anorectal melanoma: surgical management guidelines according to tumour thickness. Br J Cancer. 2003;89(11):2019-22. http://dx.doi.org/10.1038/sj.bjc.6601409
  10. Ozgüroglu M, Ozaras R, Tahan V, Demirkesen C, Demir G, Dogusoy G, et al. Anorectal melanoma metastatic to the breast. J Clin Gastroenterol. 1999;29(2):197-9. http://dx.doi.org/10.1097/00004836-199909000-00021
  11. Thibault C, Sagar P, Nivatvongs S, Ilstrup DM, Wolff BG. Anorectal melanoma- an incurable disease?. Dis Colon Rectum. 1997;40(6):661-8. http://dx.doi.org/10.1007/BF02140894
  12. Hillenbrand A, Barth TF, Henne-Bruns D, Formentini A. Anorectal amelanotic melanoma. Colorectal Dis. 2008;10(6):612-5. http://dx.doi.org/10.1111/j.1463-1318.2007.01400.x
  13. Pantalone D, Taruffi F, Paolucci R, Liguori P, Rastrelli M, Andreoli F. Malignant melanoma of the rectum. Eur J Surg. 2000;166(7):583-4. http://dx.doi.org/10.1080/110241500750008709
  14. Cooper PH, Mills SE, Allen MS Jr. Malignant melanoma of the anus: report of 12 patients and analysis of 255 additional cases. Dis Colon Rectum. 1982;25(7):693-703. http://dx.doi.org/10.1007/BF02629543
  15. N, T. (2017). Mau nanya dong dok. [online] Mau nanya dong dok. Available at: https://nanyadongdok.blogspot.com [Accessed 2 Jul. 2017].
  16. Poggi SH, Madison JF, Hwu WJ, Bayar S, Salem RR. Colonic melanoma, primary or regressed primary. J Clin Gastroenterol. 2000;30(4):441-4. http://dx.doi.org/10.1097/00004836-200006000-00019
  17. Stoidis CN, Spyropoulos BG, Misiakos EP, Fountzilas CK, Paraskeva PP, Fotiadis CI. Diffuse anorectal melanoma; review of the current diagnostic and treatment aspects based on a case report. World J Surg Oncol. 2009;7:64. http://dx.doi.org/10.1186/1477-7819-7-64
  18. Ulmer A, Metzger S, Fierlbeck G. Successful palliation of stenosing anorectal melanoma by intratumoral injections with natural interferon-beta. Melanoma Res. 2002;12(4):395-8. http://dx.doi.org/10.1097/00008390-200208000-00013
  19. Yeh JJ, Weiser MR, Shia J, Hwu WJ. Response of stage IV anal mucosal melanoma to chemotherapy. Lancet Oncol. 2005;6(6);438-9. http://dx.doi.org/10.1016/S1470-2045(05)70212-6
  20. Belli F, Gallino G, Tragni G, Andreola S, Leo E. Surgical and pathological prognostic factors in anorectal melanoma: The experience of the National Cancer Institute of Milano. Proceedings 12th Congress of the European Society of Surgical Oncology. Budapest; 2004:77.





Copyright (c) 2015 Somak Das, Tuhin S. Mandal, Souvik Paul, Purnendu Datta, Aloke K. Sinhababu

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All articles and issues in Medical Journal of Indonesia have unique DOI number registered in Crossref.
 
Romeo