Current situation of Helicobacter pylori infection in Indonesia

  • Ari F. Syam Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
Keywords: current situation, Helicobacter pylori infection, prevalence, risk factor
Abstract viewed: 3856 times
PDF downloaded: 1903 times
HTML downloaded: 175 times
EPUB downloaded: 115 times

Abstract

The epidemiology of Helicobacter pylori (H. pylori) has been changing over the past decades. Indonesia was reported have a low prevalence of H. pylori infection compared to other countries in Asia. Some studies in Indonesia have evaluated that poor sanitation, age, religion, ethnicity are the risk factors for H. pylori infection. Compared to other diagnostic tests, the urine test will be reliable for the detection of H. pylori in Indonesia because it is non-invasive and low cost with high accuracy. Although we have already performed studies on the prevalence of H. pylori infection in several ethnics, we still have some questions that remain unclear regarding H. pylori infection in Indonesia. Therefore, we have a need to build a H. pylori center that provide facilities for culturing, evaluating antibiotic resistance, and obtaining the genotype information that may explain the differences in H. pylori infection among ethnic groups in Indonesia.

References

  1. Indonesia: Estimated age-standardized incidence and mortality rates: both sexes. [Internet] 2012 [cited 2016 Jan 20]. Available from: www. http://globocan.iarc.fr/Pages/fact_sheets_population.aspx

  2. Makmun D. Present status of endoscopy, therapeutic endoscopy and the endoscopy training system in Indonesia. Dig Endosc. 2014;26(Suppl2):2–9. https://doi.org/10.1111/den.12245

  3. Leow AH, Lim YY, Liew WC, Goh KL. Time trends in upper gastrointestinal diseases and Helicobacter pylori infection in a multiracial Asian population--a 20-year experience over three time periods. Aliment Pharmacol Ther. 2016;43(7):831–7. https://doi.org/10.1111/apt.13550

  4. Syam AF, Miftahussurur M, Makmun D, Nusi IA, Zain LH, Zulkhairi, et al. Risk factors and prevalence of Helicobcater pylori in five largest islands of Indonesia: a preliminary study. PLoS ONE;10(11):e0140186. https://doi.org/10.1371/journal.pone.0140186

  5. Darnindro N, Syam AF, Fauzi A, Rumende CM. Seroprevalence and socio-demographic factors of Helicobcater pylori infection in patients with dyspepsia in Kalibaru primary health care north Jakarta. Acta Med Indones. 2015;47(4):297–303.

  6. Tokudome S, Samsuria Soeripto WD, Triningsih FX, Suzuki S, Hosono A, Triono T, et al. Helicobacter pylori infection appears essential for stomach carcinogenesis: observations in Semarang, Indonesia. Cancer Sci. 2005;96(12):873–5. https://doi.org/10.1111/j.1349-7006.2005.00122.x

  7. Abdullah M, Ohtsuka H, Rani AA, Sato T, Syam AF, Fujino MA. Helicobacter pylori infection and gastropathy: a comparison between Indonesian and Japanese patients. World J Gastroenterol. 2009;15(39):4928–31. https://doi.org/10.3748/wjg.15.4928

  8. Miftahussurur M, Shiota S, Suzuki R, Matsuda M, Uchida T, Kido Y, et al. Identification of Helicobacter pylori infection in symptomatic patients in Surabaya, Indonesia, using five diagnostic tests. Epidemiol Infect. 2015;143(5):986–96. https://doi.org/10.1017/S095026881400154X

  9. Syam AF, Rani AA, Abdullah M, Manan C, Makmun D, Simadibrata D, et al. Accuracy of Helicobacter pylori stool antigen for the detection of Helicobacter pylori infection in dyspeptic patients. World J Gastroenterol. 2005;11(3):386–8. https://doi.org/10.3748/wjg.v11.i3.386

  10. Saragih JB, Akbar N, Syam AF, Sirait S, Himawan S, Soetjahyo E. Incidence of Helicobacter pylori infection and gastric cancer: an 8-year hospital based study. Acta Med Indones. 2007;39(2):79–81.

  11. Syam AF, Abdullah M, Rani AA, Nurdjanah S, Adi P, Djumhana A, et al. Evaluation of the use of rapid urease test: Pronto Dry to detect H. pylori in patients with dyspepsia in several cities in Indonesia. World J Gastroenterol. 2006;12(38):6216–8. https://doi.org/10.3748/wjg.v12.i38.6216

  12. Syam AF, Miftahussurur M, Uwan WB, Simanjuntak D, Uchida T, Yamaoka Y. Validation of urine test for detection of Helicobacter pylori infection in Indonesian population. BioMed Res Int. 2015;2015(152823):1–6. https://doi.org/10.1155/2015/152823

  13. Miftahussurur M, Tuda J, Suzuki R, Kido Y, Kawamoto F, Matsuda M, et al. Extremely low Helicobacter pylori prevalence in North Sulawesi, Indonesia, and identification of a Maori-tribe-type strain: a cross-sectional study. Gut Pathog. 2014;6(42):1–8. Doi: 10.1186/s13099-014-0042-0

Published
2017-01-25
How to Cite
1.
Syam AF. Current situation of <em>Helicobacter pylori</em&gt; infection in Indonesia. Med J Indones [Internet]. 2017Jan.25 [cited 2024May3];25(4):263-6. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/1408
Section
Brief Communication