Lepromatous leprosy mimicking systemic lupus erithematosus: a case report

  • Niken Kusumaningrum Department of Dermatology and Venereology, Faculty of Medicine, Universitas Gadjah Mada, Dr. Sardjito Hospital, Yogyakarta
  • Schandra Purnamawati Department of Dermatology and Venereology, Faculty of Medicine, Universitas Gadjah Mada, Dr. Sardjito Hospital, Yogyakarta; aculty of Medicine, Universitas Jenderal Soedirman, Purwokerto
  • Dwi Retno Adi Winarni Department of Dermatology and Venereology, Faculty of Medicine, Universitas Gadjah Mada, Dr. Sardjito Hospital, Yogyakarta
  • Hardyanto Soebono Department of Dermatology and Venereology, Faculty of Medicine, Universitas Gadjah Mada, Dr. Sardjito Hospital, Yogyakarta
Keywords: lepromatous leprosy, systemic lupus erythematosus
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Abstract

The clinical manifestations of leprosy are highly variable, and the disease is notorious for being “a great imitator” of several other conditions. Leprosy may manifest with a variety of phenomena resembling those of autoimmune diseases. Herein, we report a 33-year-old male presenting with wounds on his left leg and hyperpigmented skin lesions all over his body. Six years earlier, the patient was diagnosed with systemic lupus erythematosus (SLE). However, therapy for SLE did not control his symptoms; instead, the patient developed features of leprosy, such as anesthetic skin lesions, nerve enlargement, and tenderness. Tests for antinuclear antibodies and anti-double stranded DNA antibodies were negative. Slit-skin smear showed a bacterial index of 6+ and morphological index of 10 %. Lupus band test results were negative. Histological findings were compatible with lepromatous leprosy. The clinical and serological similarities between leprosy and SLE may lead to erroneous diagnosis. Thus, clinicians should be aware of this characteristic for correct diagnosis.

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Published
2019-05-08
How to Cite
1.
Kusumaningrum N, Purnamawati S, Winarni DRA, Soebono H. Lepromatous leprosy mimicking systemic lupus erithematosus: a case report. Med J Indones [Internet]. 2019May8 [cited 2020Jun.5];28(1):77-1. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/1793
Section
Case Report/Series