Autologus normovolemic and hypervolemic hemodilution during surgery using 6% dextran 70 and lactated ringer solution: impact on mean arterial pressure, heart rate, hemoglobin and hematocrite (A preliminary study)
Keywords:
Acute normovolenic hemodilution, Acute normovolenic hemodiluti, dextran 70, lactated ringer solution, microsirculation
Abstract viewed: 477 times
PDF downloaded: 515 times
Abstract
Autologous normovolemic hemodilution (ANH) is one of the methods to conserve blood donor (homologous). The decrease in hemoglobin (Hb) due to bleeding in major surgery will be minimized and the hematocrite (Hct) will be adjusted accordingly by this method. However, due to its impractical clinical application, another simpler hemodilution method is used, i.e. hypervolemic hemodilution (HHD), using 6% dextran 70 and lactated Ringer solutions. The aim of this randomized comparative study was to investigate the impacts of both hemodilution methods (ANH and HHD) on mean arterial pressure (MAP), heart rate (HR), hemoglobin (Hb) and hematocrite (Hct) in anesthetized patients undergoing major surgery. Fourteen (14) women fulfilling the inclusion and exclusion criteria were divided into 2 groups. Seven (7) women received ANH and seven (7) women received HHD method. There were significant statistical differences (P<0.05) between ANH and HHD groups in MAP and Hct after 1 minute (86.3±9.1 vs. 99.1±6.4 on MAP) and (27.3±1.7 vs. 31.5±4.4 on Hct) and after 20 minutes (87.7±7.3 vs. 98.3±6.8 on MAP) and (27.4±1.7 vs. 3.6±4.8 on Hct) post-hemodilution respectively. There was no difference in HR and Hb. No statistical difference between the four parameters tested after 120 minutes post-hemodilution. It may be concluded that both methods worth to be used in clinical setting although further studies are required. (Med J Indones 2006; 15:246-50)
Published
2006-11-01
How to Cite
1.
Dachlan R, Kristanto K, Suprayogi E. Autologus normovolemic and hypervolemic hemodilution during surgery using 6% dextran 70 and lactated ringer solution: impact on mean arterial pressure, heart rate, hemoglobin and hematocrite (A preliminary study). Med J Indones [Internet]. 2006Nov.1 [cited 2024Apr.26];15(4):246-50. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/242
Section
Clinical Research
Copyright (c) 2006 Ruswan Dachlan, Kristanto Kristanto, Eko Suprayogi
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with Medical Journal of Indonesia agree to the following terms:
- Authors retain copyright and grant Medical Journal of Indonesia right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial License that allows others to remix, adapt, build upon the work non-commercially with an acknowledgment of the work’s authorship and initial publication in Medical Journal of Indonesia.
- Authors are permitted to copy and redistribute the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Medical Journal of Indonesia.