Cholestasis sepsis at neonatology ward and neonatal Intensive Care Unit Cipto Mangunkusumo Hospital 2007 : incidence, mortality rate and associated risk factors

  • Kadim S. Bachtiar Department of Child Health, Faculty of Medicine University of Indonesia,Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Hanifah Oswari Division of Gastrohepatology, Department of Child Health, 2 Faculty of Medicine University of Indonesia,Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Jose R.L. Batubara Division of Endocrinology , Department of Child Health, Faculty of Medicine University of Indonesia,Cipto
  • Idham Amir Division of Neonatology, Department of Child Health, Faculty of Medicine University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Abdul Latief Division of Pediatric Intensive Care Unit, Department of Child Health, Faculty of Medicine University of Indonesia,Cipto Mangunkusumo Hospital, Jakarta, Indonesia
  • Kemas Firman Division of Radiology, Department of Child Health, Faculty of Medicine University of Indonesia,Cipto Mangunkusumo Hospital, Jakarta, Indonesia
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Abstract

Cholestatic jaundice represents serious pathological condition. Septic-cholestasis is a kind of hepato-cellular cholestasis that occured during or after sepsis caused by biliary flow obstruction. This is a cohort study from February to June 2007 on neonatal sepsis patients at Neonatology ward Department of Child Health Faculty of Medicine University of Indonesia-Cipto Mangunkusumo General National Hospital. Aim of this study is to find out the incidence of intrahepatic cholestasis in neonatal sepsis, associated risk factors, and mortality rate in neonatal cholestasis-sepsis. From 138 neonatal sepsis patients, the incidence of intrahepatic cholestasis is 65.9%. None of the risk factors tested in this study showed statistically significant result. Mortality rate of neonatal cholestasis-sepsis is 52.8%. (Med J Indones 2008; 17: 107-13)

Keywords: cholestasis intrahepatic, neonatal sepsis, cholestasis sepsis, conjugated hyperbilirubinemia

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Published
2008-05-01
How to Cite
1.
Bachtiar KS, Oswari H, Batubara JR, Amir I, Latief A, Firman K. Cholestasis sepsis at neonatology ward and neonatal Intensive Care Unit Cipto Mangunkusumo Hospital 2007 : incidence, mortality rate and associated risk factors. Med J Indones [Internet]. 2008May1 [cited 2019Jul.24];17(2):107-13. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/306
Section
Clinical Research