Short-term intravenous zoledronic acid in severe osteogenesis imperfecta : A report of three siblings of children

Authors

  • Hadyanto Lim
  • Umar Zein
  • Yahwardiah Siregar
  • Blondina Marpaung
  • Jaminsen Sinaga

DOI:

https://doi.org/10.13181/mji.v17i2.310

Keywords:

zoledronic acid, osteogenesis imperfecta, side effects

Abstract

This report documented the clinical and biochemical side effects on the first dose of intravenous zoledronic acid therapy in three siblings with severe osteogenesis imperfecta. Zoledronic acid was administered in 50 ml 0.9% saline solution over a period of 30 minutes. All patients had fever during the first 6 to 48 hours after the first infusion. There were no renal side effects, apart from asymptomatic hypocalcemia and hypophosphatemia at 48 and 72 hours after zoledronic acid infusion. The minimal clinical side effects were easily manageable. (Med J Indones 2008; 17: 127-30)

 

Downloads

Download data is not yet available.

Downloads

Published

2008-05-01

How to Cite

1.
Lim H, Zein U, Siregar Y, Marpaung B, Sinaga J. Short-term intravenous zoledronic acid in severe osteogenesis imperfecta : A report of three siblings of children. Med J Indones [Internet]. 2008May1 [cited 2024Dec.11];17(2):127-30. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/310

Issue

Section

Clinical Research
Abstract viewed = 660 times