A randomized, controlled, cross-over study of the safety and efficacy of superabsorbent diaper for babies with mild-to-moderate diaper rash
DOI:
https://doi.org/10.13181/mji.oa.203630Keywords:
efficacy, safety, super-absorbent diaperAbstract
BACKGROUND Super-absorbent diaper is a disposable diaper with new technology which has a soft-airy structure, breathable sheet, and rich absorbent core. This study aimed to compare the safety and efficacy of super-absorbent diaper with standard absorbent diaper.
METHODS A single-blinded, randomized, controlled, cross-over study was performed in 324 months babies. A safety study was performed in 113 babies without diaper rash (group A: super-absorbent to standard and B: standard to super-absorbent) and efficacy study in 59 babies with mild-to-moderate diaper rash (group C: super-absorbent to standard and D: standard to super-absorbent). Each group used super-absorbent or standard diaper for 2 weeks. Skin assessment scores (SAS) were recorded at baseline, week-2, and week-4. Non-parametric tests were used to analyze the data.
RESULTS In the safety study, there was no significant increase of SAS in group A at week-2 and -4, but in group B there was a significant increase of SAS (1.9 to 4.1, p = 0.001) at week-2 with a significant reduction at week-4 (4.1 to 2.2, p<0.001). In the efficacy study, there was a reduction of SAS at week-2 in group C (p = 0.07) and D (p = 0.05). However, SAS increased in group C (6.4 to 8.3, p = 0.2) and decreased in group D (8.6 to 6.1, p = 0.13) at week-4. Super-absorbent diaper showed a significant reduction of SAS in the pubic areas (1.43 to 0.73, p<0.011).
CONCLUSIONS The new super-absorbent diaper is safe to use and may have efficacy in the improvement of skin conditions and diaper rash, especially in the pubic areas.
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References
Hunt R, Chang MW, Shah KN. Neonatal dermatology. In: Kang S, Amagai M, Bruckner AL, Enk AH, Margolis DJ, McMichael AJ, et al, editors. Fitzpatrick's Dermatology. 9th ed. New York: McGraw Hill; 2019. p. 1727-42.
Stamatas GN, Tierney NK. Diaper dermatitis: etiology, manifestations, prevention, and management. Pediatr Dermatol. 2014;31(1):1-7. https://doi.org/10.1111/pde.12245
Chirac A, Brzezinski P, Chiriac AE, Foia L, Pinteala T. Autosensitisation (autoeczematisation) reactions in a case of diaper dermatitis candidiasis. Niger Med J. 2014;55(3):274-5. https://doi.org/10.4103/0300-1652.132070
Blume-Peytavi U, Hauser M, Lünnemann L, Stamatas GN, Kottner J, Garcia Bartels N. Prevention of diaper dermatitis in infants-a literature review. Pediatr Dermatol. 2014;31(4):413-29. https://doi.org/10.1111/pde.12348
Odio M, Thaman L. Diapering, diaper technology, and diaper area skin health. Pediatr Dermatol. 2014;31 Suppl 1:9-14. https://doi.org/10.1111/pde.12501
Helmes CT, O'connor R, Sawyer L, Young S. Disposable diaper absorbency: improvements via advanced designs. Clin Pediatr. 2014;53(9 Suppl):14S-6S. https://doi.org/10.1177/0009922814540377
Counts, JL, Helmes CT, Kenneally D, Otts DR. Modern disposable diaper construction: innovations in performance help maintain healthy diapered skin. ClinPediatr. 2014;53(9 suppl):10S-3S. https://doi.org/10.1177/0009922814540376
Yuan C, Takagi R, Yao XQ, Xu YF, Ishida K, Toyoshima H. Comparison of the effectiveness of new material diapers versus standard diapers for the prevention of diaper rash in Chinese babies: a double-blinded, randomized, controlled, cross-over study. Biomed Res Int. 2018;2018:5874184. https://doi.org/10.1155/2018/5874184
Maesey M. Indonesia: a vulnerable country in the face of climate change. Global Majority E-Journal. 2010;1(1):31-45.
Burdall O, Willgres L, Goad N. Neonatal skin care: development in care to maintain neonatal barrier function and prevention of diaper dermatitis. Pediatr Dermatol. 2019;36(1):31-5. https://doi.org/10.1111/pde.13714
Dey S, Kenneally D, Odio M, Hatzopoulos I. Modern diaper performance: construction, materials, and safety review. Int J Dermatol. 2016;55 Suppl 1:18-20. https://doi.org/10.1111/ijd.13333
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