Primary malignant giant cell tumor of the patella: report of a rare case

Achmad F. Kamal; Errol U. Hutagalung; Saukani Gumay; Yogi Prabowo; Yanuarso Yanuarso

doi:10.13181/mji.v22i4.607

Authors

Achmad F. Kamal Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Errol U. Hutagalung Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Saukani Gumay Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Yogi Prabowo Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Yanuarso Yanuarso Department of Orthopaedic and Traumatology, Gatot Subroto Central Army Hospital, Jakarta, Indonesia

DOI:

https://doi.org/10.13181/mji.v22i4.607

Keywords:

Limb sparing surgery, primary malignant GCT, total patellectomy

Abstract

Primary malignant giant cell tumor (GCT) at the patella bone is a very rare case. It is a high-grade sarcoma characterized by a lesion in which there are areas of synchronous high-grade sarcomatous next to areas of benign GCT. A limb sparing approach is applicable to virtually any bone lesion, whether low grade or high grade. We report a case with primary malignant GCT at the patella, from diagnostic to detailed limb sparing surgery procedure. Fifteen months after surgery, the patient had a good functional outcome without local recurrence and distant metastasis. (Med J Indones. 2013;22:238-42. doi: 10.13181/mji.v22i4.607)

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References

Murphey MD, Nomikos GC, Flemming DJ, Gannon FH, Temple HT, Kransdorf MJ. From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: radiologic-pathologic correlation. Radiographics. 2001;21(5):1283-309. http://dx.doi.org/10.1148/radiographics.21.5.g01se251283

Unni KK. Giant cell tumor (osteoclastoma). In: Dahlin's bone tumors - general aspects and data on 11,087 cases. 5th edition. Philadelphia: Lippincott Williams & Wilkins; 1996.p.263-82.

Unni KK, Inwards CY, Bridge JA, Kindblom L-G, Wold LE. AFIP atlas of tumour pathology series 4: tumours of the bones and joints. Washington: AFIP-ARP; 2005.

Unni KK. Malignancy in giant cell tumor of bone. In: Dahlin's bone tumors - general aspects and data on 11,087 cases. 5th edition. Philadelphia: Lippincott Williams & Wilkins; 1996.p.285-9.

Bullough PG, Bansal M. Malignancy in giant cell tumour. In: Fletcher CDM, Unni KK, Mertens F, editors. World health organization classification of tumours, pathology, and genetics of tumours of soft tissue and bone. Geneva: IARC Press; 2002.p.313.

Sung HW, Kuo DP, Shu WP, Chai YB, Liu CC, Li SM. Giant-cell tumor of bone: analysis of two hundred and eight cases in Chinese patients. J Bone Joint Surg Am. 1982;64(5):755-61.

Reddy CRRM, Rao PS, Rajakumari K. Giant-cell tumors of bone in south India. J Bone Joint Surg Am. 1974;56(3):617-9.

Manaster BJ, Doyle AJ. Giant cell tumors of bone. Radiol Clin North Am. 1993;31(2):299-323.

Larsson SE, Lorentzon R, Boquist L. Giant-cell tumor of bone. A demographic, clinical, and histopathological study of all cases recorded in the Swedish Cancer Registry for the years 1958 through 1968. J Bone Joint Surg Am. 1975;57(2):167-73.

Hong SW, Choi HY. Malignant giant cell tumor of the skull. J Korean Neurosurg Soc. 2004;36(4):324-7.

Greenspan A. Orthopedic imaging: a practical approach. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2004.p.136-54.

Armen KK, Nolan SK. Lower extremity reconstruction. In: Charles HT, editor. Grabb and Smith's plastic surgery. 6th ed. Washington: Lippincott Williams & Wilkins; 2007.p.1031-49.

Domovitov SV, Healey JH. Primary malignant giant-cell tumor of bone has high survival rate. Ann Surg Oncol. 2010;17(3):694-701. http://dx.doi.org/10.1245/s10434-009-0803-z