Safety of augmentation cystoplasty in patients with bladder abnormalities undergoing renal transplantation: a systematic review
BACKGROUND Augmentation cystoplasty (AC) has been recently proposed to improve a bladder condition before or after a renal transplantation for an optimal allograft function. Until now, AC in adults with end-stage renal disease (ESRD) is uncommon and rarely practiced. This study aimed to investigate the safety of AC in patients with bladder abnormalities who required renal transplantation.
METHODS Studies of patients with ESRD and abnormal bladder who underwent AC were searched in ProQuest, PubMed, EBSCO, and Cochrane Library online databases. Only studies published in English from January 1985 to May 2020 were included. The keywords used were renal transplantation, bladder dysfunction, cystoplasty, and their synonyms. Data were extracted by two independent authors who selected, screened, and assessed the articles’ eligibility and quality. The outcomes were graft survival rate and complications of AC.
RESULTS A total of 19 articles were included. AC improved an intravesical pressure, a bladder capacity, and a compliance in patients with ESRD and bladder abnormalities, allowing patients to undergo the renal transplantation. Even though AC in patients with renal transplantation resulted in a significantly higher urinary tract infection rate than patients who underwent renal transplantation only, performing AC after renal transplantation was considered safe.
CONCLUSIONS AC was considered safe for patients with bladder abnormalities who underwent renal transplantation.
Traxel E, DeFoor W, Minevich E, Reddy P, Alam S, Reeves D, et al. Low incidence of urinary tract infections following renal transplantation in children with bladder augmentation. J Urol. 2011;186(2):667-71. https://doi.org/10.1016/j.juro.2011.03.155
Fontaine E, Gagnadoux MF, Niaudet P, Broyer M, Beurton D. Renal transplantation in children with augmentation cystoplasty: long-term results. J Urol. 1998;159(6):2110-3. https://doi.org/10.1016/S0022-5347(01)63287-7
Higgins JP, Green S, editors. Cochrane handbook for systematic reviews of interventions. Chichester: John Wiley & Sons; 2008. https://doi.org/10.1002/9780470712184
Basiri A, Otookesh H, Hosseini R, Simforoosh N, Moghaddam H. Kidney transplantation before or after augmentation cystoplasty in children with high-pressure neurogenic bladder. BJU Int. 2009;103(1):86-8. https://doi.org/10.1111/j.1464-410X.2008.08081.x
Pereira PL, Rodriguez RO, Camblor CF, Urrutia MJ, Romera RL, Espinosa L, et al. Renal transplant outcome in children with an augmented bladder. Front Pediatr. 2013;1:42. https://doi.org/10.3389/fped.2013.00042
Zaragoza MR, Ritchey ML, Bloom DA, McGuire EJ. Enterocystoplasty in renal transplantation candidates: urodynamic evaluation and outcome. J Urol. 1993;150(5 Part 1):1463-6. https://doi.org/10.1016/S0022-5347(17)35810-X
Blanco M, Medina J, Pamplona M, Miranda N, Gonzalez E, Aguirre JF, et al. Outcome of renal transplantation in adult patients with augmented bladders. Transplant Proc. 2009;41(6):2382-4. https://doi.org/10.1016/j.transproceed.2009.06.106
Garat JM, Caffaratti J, Angerri O, Bujons A, Villavicencio H. Kidney transplants in patients with bladder augmentation: correlation and evolution. Int Urol Nephrol. 2009;41:1-5. https://doi.org/10.1007/s11255-006-9164-8
Taghizadeh AK, Desai D, Ledermann SE, Shroff R, Marks SD, Koffman G, et al. Renal transplantation or bladder augmentation first? A comparison of complications and outcomes in children. BJU Int. 2007;100(6):1365-70. https://doi.org/10.1111/j.1464-410X.2007.07096.x
Power RE, O'Malley KJ, Khan MS, Murphy DM, Hickey DP. Renal transplantation in patients with an augmentation cystoplasty. BJU Int. 2007 Jun 25;86(1):28-31. https://doi.org/10.1046/j.1464-410x.2000.00705.x
Dinckan A, Turkyilmaz S, Tekin A, Erdogru T, Kocak H, Mesci A, et al. Simultaneous augmentation ileo-cystoplasty in renal transplantation. Urology. 2007;70(6):1211-4. https://doi.org/10.1016/j.urology.2007.09.045
Rigamonti W, Capizzi A, Zacchello G, Capizzi V, Zanon GF, Montini G, et al. Kidney transplantation into bladder augmentation or urinary diversion: long-term results. Transplantation. 2005;80(10):1435-40. https://doi.org/10.1097/01.tp.0000174342.19265.f4
Nahas WC, Mazzucchi E, Arap MA, Antonopoulos IM, Neto ED, Ianhez LE, et al. Augmentation cystoplasty in renal transplantation: a good and safe option--experience with 25 cases. Urology. 2002;60(5):770-4. https://doi.org/10.1016/S0090-4295(02)01947-7
Yamazaki Y, Tanabe K, Ota T, Ito K, Toma H. Renal transplantation into augmented bladders. Int J Urol. 1998;5(5):423-7. https://doi.org/10.1111/j.1442-2042.1998.tb00381.x
Aki FT, Besbas N, Ozcan O, Bakkaloglu A, Erkan I, Bakkaloglu M, et al. Renal transplantation in children with augmentation enterocystoplasty. Transplant Proc. 2006;38(2):554-5. https://doi.org/10.1016/j.transproceed.2006.01.008
Thomalla JV, Mitchell ME, Leapman SB, Filo RS. Renal transplantation into the reconstructed bladder. J Urol. 1989;141(2):265-8. https://doi.org/10.1016/S0022-5347(17)40736-1
Martín MG, Castro SN, Castelo LA, Abal VC, Rodríguez JS, Novo JD. Enterocystoplasty and renal transplantation. J Urol. 2001;165(2):393-6. https://doi.org/10.1097/00005392-200102000-00009
Tan LR, Tiong HY. Ureteric implantation into the bowel portion of augmented bladders during kidney transplantation: a review of urological complications and outcomes. ANZ J Surg. 2019;89(7-8):930-4. https://doi.org/10.1111/ans.14828
Selli C, Doggweikr R, Carmellini M, Boggi U, Mosca F. Renal transplantation following Reduction of ileocecocystoplasty performed 9 years earlier for undiversion. Urol Int. 1997;59(3):182-5. https://doi.org/10.1159/000283058
Farouk K, Bano U, Gondal M. Renal transplant in a patient with augmentation cystoplasty. J Ayub Med Coll Abbottabad. 2007;19(3):85-8.
Capozza N, Torino G, Collura G, Battaglia S, Guzzo I, Caione P, et al. Renal transplantation in patients with "valve bladder": is bladder augmentation necessary? Transplant Proc. 2010;42(4):1069-73. https://doi.org/10.1016/j.transproceed.2010.03.040
Barnett M, Bruskewitz R, Glass N, Sollinger H, Uehling D, Belzer FO. Long-term clean intermittent self-catheterization in renal transplant recipients. J Urol. 1985;134(4):654-7. https://doi.org/10.1016/S0022-5347(17)47370-8
Benfield MR, McDonald R, Sullivan EK, Stablein DM, Tejani A. The 1997 annual renal transplantation in children report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). Pediatr Transplant. 1999;3(2):152-67. https://doi.org/10.1034/j.1399-3046.1999.00011.x
Nahas WC, Lucon M, Mazzucchi E, Antonopoulos IM, Piovesan AC, Neto ED, et al. Clinical and urodynamic evaluation after uretero cystoplasty and kidney transplantation. J Urol. 2004;171(4):1428-31. https://doi.org/10.1097/01.ju.0000118761.88563.70
Lojanapiwat B, Mital D, Fallon L, Koolpe H, Raja R, Badosa F, et al. Management of ureteral stenosis after renal transplantation. J Am Coll Surg. 1994;179(1):21-4.
Romero Pérez P, Mira Llinares A. [Renal and ureteral complications of urethral stenosis]. Actas Urol Esp. 1995;19(6):432-40. Spanish.
Daher P, Zeidan S, Riachy E, Iskandarani F. Bladder augmentation and/or continent urinary diversion: 10-year experience. Eur J Pediatr Surg. 2007;17(2):119-23. https://doi.org/10.1055/s-2007-965027
Slagt IK, IJzermans JN, Alamyar M, Verhagen PC, Weimar W, Roodnat JI, et al. Long-term outcome of kidney transplantation in patients with a urinary conduit: a case-control study. Int Urol Nephrol. 2013;45(2):405-411 https://doi.org/10.1007/s11255-013-0395-1
Husmann DA. Long-term complications following bladder augmentations in patients with spina bifida: bladder calculi, perforation of the augmented bladder and upper tract deterioration. Transl Androl Urol. 2016;5(1):3-11. https://doi.org/10.3978/j.issn.2223-4683.2015.12.06
Harding C, Veeratterapillay R, Thorpe A. Augmentation cystoplasty: contemporary indications, techniques and complications. Indian J Urol. 2013;29(4):322. https://doi.org/10.4103/0970-1591.120114
Kispal Z, Balogh D, Erdei O, Kehl D, Juhasz Z, Vastyan AM, et al. Complications after bladder augmentation or substitution in children: a prospective study of 86 patients. BJU Int. 2011;108(2):282-9. https://doi.org/10.1111/j.1464-410X.2010.09862.x
Husmann DA, Rathbun SR. Long-term follow up of enteric bladder augmentations: the risk for malignancy. J Pediatr Urol. 2008;4(5):381-5. https://doi.org/10.1016/j.jpurol.2008.06.003
Sheldon CA, Gonzalez R, Burns MW, Gilbert A, Buson H, Mitchell ME. Renal transplantation into the dysfunctional bladder: the role of adjunctive bladder reconstruction. J Urol. 1994;152(3):972-5. https://doi.org/10.1016/S0022-5347(17)32633-2
Mahdavi Zafarghandi R, Zeraati A, Tavakoli M, Kalani Moghaddam F, Mahdavi Zafarghandi M. Comparison of enterocystoplasty and ureterocystoplasty before kidney transplantation. Int J Organ Transplant Med. 2010;1(4):177-82.
Nahas WC, Mazzucchi E, Antonopoulos I, Denes FT, David-Neto E, Ianhez LE, et al. End-stage renal disease and bladder dysfunction: algorithm for renal transplantation. Transplant Proc. 2001;33(6):2984-5. https://doi.org/10.1016/S0041-1345(01)02281-3
Copyright (c) 2021 Bobby Sutojo, Gampo Alam Irdam
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with Medical Journal of Indonesia agree to the following terms:
- Authors retain copyright and grant Medical Journal of Indonesia right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial License that allows others to remix, adapt, build upon the work non-commercially with an acknowledgment of the work’s authorship and initial publication in Medical Journal of Indonesia.
- Authors are permitted to copy and redistribute the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Medical Journal of Indonesia.