β-endorphin response to aerobic and anaerobic exercises in Wistar male rats

Authors

  • Rostika Flora Faculty of Public Health, Universitas Sriwijaya, Palembang, Indonesia https://orcid.org/0000-0002-2904-0407
  • Mohammad Zulkarnain Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia https://orcid.org/0000-0002-0966-5100
  • Sukirno Study Program of Sport and Health Education, Faculty of Teacher Training and Education, Universitas Sriwijaya, Palembang, Indonesia

DOI:

https://doi.org/10.13181/mji.oa.203569

Keywords:

aerobic exercise, anaerobic exercise, β-endorphin
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Abstract

BACKGROUND Physical exercise is strongly associated with the release of β-endorphin. It is assumed that the type and intensity of physical exercise contributes to the release of β-endorphin. This study aimed to compare levels of β-endorphin in brain tissue in response to aerobic and anaerobic physical exercise.

METHODS This study was an experimental laboratory study using 35 male Wistar rats divided into one control group and two physical exercise treatment groups: aerobic and anaerobic. Physical exercise was conducted on an animal treadmill running at aspeed of 20 m/min for 30 min of aerobic exercise and 35 m/min with 1-min intervals every 5 min for 20 min for anaerobic exercises. Each aerobic and anaerobic exercise group was furtherly classified into three subgroups (1×/week, 3×/week, and 7×/week). β-endorphin levels were determined using enzyme-linked immunosorbent assay. The data were analyzed using independent t-test and one-way analysis of variance.

RESULTS The highest mean of β-endorphin level was found in the weekly exercise (54.45 [1.41] pg/ml) of aerobic exercise group and daily exercise (70.50 [11.67] pg/ml) of anaerobic exercise group. Mean of β-endorphin level in control group was 33.34 (3.54) pg/ml. A significant increased of β-endorphin mean level (p<0.001) was found in all aerobic and anaerobic exercise groups except the aerobic exercise 7×/week group
(37.37 [6.30] pg/ml) compared to control.

CONCLUSIONS Both aerobic and anaerobic physical exercise conducted for 6 weeks could increase the level of β-endorphin in brain tissue.

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References

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Published

2020-10-05

How to Cite

1.
Flora R, Zulkarnain M, Sukirno. β-endorphin response to aerobic and anaerobic exercises in Wistar male rats . Med J Indones [Internet]. 2020Oct.5 [cited 2024Dec.22];29(3):245-9. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/3569

Issue

Section

Basic Medical Research
Abstract viewed = 1629 times
PDF downloaded = 1080 times HTML downloaded = 179 times EPUB downloaded = 193 times