Highly active antiretroviral therapy adherence and its determinants in selected regions in Indonesia

Felix F. Widjaja, Caroline G. Puspita, Ferdi Daud, Ienag Yudhistrie, Marita R. Tiara, Christopher S. Suwita, Ekachaeryanti Zain, Lailatul Husna, Samsuridjal Djauzi



DOI: https://doi.org/10.13181/mji.v20i1.429

Abstract


Background: Highly active antiretroviral therapy (HAART) can reduce morbidity and mortality of HIV-infected patients. However, it depends upon adherence to medication. The objective of this study was to examine the adherence to HAART and to evaluate individual patient characteristics i.e. self-efficacy, depression level, and social support and to finally determine HAART adherence in selected regions in Indonesia.

Methods: This cross-sectional study was conducted in Jakarta, Malang, Bandung, Makasar and Banda Aceh. The subject of the study was HIV-infected patients who were older than 13 years old and had taken HAART for at least a month. They were recruited consecutively then asked how many pills they had missed during the previous month. Poor adherence can be stated if the percentage of adherence rate is below 95%. HIV treatment adherence self-efficacy scale  (HIVASES), Beck Depression Inventory (BDI-II) and Interpersonal Support Evaluation List (ISEL) was adapted to assess self-efficacy, depression level and social support, respectively.

Results: We found that 96% (n=53) of the subjects adhered to HAART. There were no associations between adherence with self-efficacy, depression level, and social support. The main cause of non-adherence in this study was ‘simply  forget’.

Conclusion: Adherence to HAART was found to be high and not associated with self-efficacy, depression level and social support in some central regions in Indonesia. (Med J Indones 2011; 20:50-5)

Keywords: adherence, depression, HAART, HIV, self-efficacy, social support


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Copyright (c) 2011 Felix F. Widjaja, Caroline G. Puspita, Ferdi Daud, Ienag Yudhistrie, Marita R. Tiara, Christopher S. Suwita, Ekachaeryanti Zain, Lailatul Husna, Samsuridjal Djauzi

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