Correlation of zinc plasma and IgM anti-PGL-1 levels among close contact of leprosy

  • Mohammad Z. Rahfiludin
  • Praba Ginandjar
  • Dina R. Pangestuti
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Abstract

Background: Previous study showed leprosy patients have low zinc status. Yet the status of zinc in close-contact, which indicated by IgM anti-PGL1 level, have not determined. The aim of the study was to determine the association of zinc plasma and IgM anti-PGL-1 levels among close contact of leprosy patients in Indonesia.

Methods: This was an observational study. Subjects were 186 close-contact leprosy patients. Measurement of zinc plasma status used atomic absorption spectrophotometer while examination of IgM anti-PGL1 level used ELISA (Polyclonal rabbit anti human IgM/HRP/(Dako®).

Results: The average level of IgM anti-PGL1 and zinc plasma were 804 unit/mL (± 439.4) and 16.6 μmol/L (± 3.5) consecutively. There was significant correlation between zinc plasma and IgM anti-PGL1 (r = - 0.230; p = 0.002).

Conclusion: There is a significant correlation between zinc plasma and IgM anti-PGL1 in close contact of leprosy (Med J Indones. 2012;21:166-9)

Keywords: IgM anti PGL-1, close contact of leprosy, zinc plasma

Published
2012-08-01
How to Cite
1.
Rahfiludin MZ, Ginandjar P, Pangestuti DR. Correlation of zinc plasma and IgM anti-PGL-1 levels among close contact of leprosy. Med J Indones [Internet]. 2012Aug.1 [cited 2020Oct.21];21(3):160-5. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/500
Section
Community Research