Indonesian local fetal-weight standard: a better predictive ability for low Apgar score of SGA neonates

  • Adly N.A. Fattah Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
  • Karina N. Pratiwi Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
  • Sulaeman A. Susilo Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
  • Jimmy S.N. Berguna Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
  • Rima Irwinda Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
  • Noroyono Wibowo Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
  • Budi I. Santoso Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
  • Jun Zhang Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health,
Xinhua Hospital,
Shanghai
Keywords: Apgar, small-for-gestational-age, standard, weight
Abstract viewed: 1331 times
PDF downloaded: 551 times

Abstract

Background: Accurate assessment of fetal growth is one of crucial components of antenatal care. A generic reference for fetal-weight and birthweight percentiles that can be easily adapted to local populations have been developed by Mikolajczyk and colleagues. This study aimed to validate our own local percentile standard by evaluating the odds ratio (OR) of low 1st and 5th minute Apgar score for small-for-gestational age (SGA) versus those not SGA.

Methods: We used the generic reference tools for fetal-weight and birthweight percentiles developed by Mikolajczyk and colleagues to create our own local standard and then defined the SGA neonates. For validation, we used the database of singleton live deliveries (2,139 birth) during January 1st to December 31st 2013 in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. We compared our reference with that of Hadlock and colleagues. For every reference, the OR of Apgar score <7 at 1st and 5th minutes for infants who were SGA versus those not estimated with bivariate and multivariate analyses.

Results: SGA found in 35% (748/2,139) and 13% (278/2,139) of neonates using the definition derived from Indonesian standard and Hadlock’s. OR of Apgar score <7 at 1st and 5th minutes were 3.45 (95% CI=2.56–4.65) and 3.05 (95% CI=1.92–4.83) for the Indonesian local fetal-weight standard compared with respectively 2.14 (95% CI=1.65–2.76) and 1.83 (95% CI=1.21–2.77) for Hadlock and collegues’ reference.

Conclusion: Indonesian local fetal-weight standard has a better ability to predict low 1st and 5th minutes Apgar scores of SGA neonates than has the Hadlock and collegues’ reference.

References

  1. Bloemenkamp KWM. Fetal growth. Int Congr Series. 2005;1279:295–301. https://doi.org/10.1016/j.ics.2005.02.067

  2. Gardosi J. Fetal growth standards: individual and global perspectives. Lancet. 2011;377(9780):1812–4. https://doi.org/10.1016/S0140-6736(11)60507-2

  3. Zhang J, Merialdi M, Platt LD, Kramer MS. Defining normal and abnormal fetal growth: promises and challenges. Am J Obstet Gynecol. 2010;202(6):522–8. https://doi.org/10.1016/j.ajog.2009.10.889

  4. Reeves S, Bernstein IM. Optimal growth modeling. Semin Perinatol. 2008;32(3):148–53. https://doi.org/10.1053/j.semperi.2007.11.001

  5. Morse K, Williams A, Gardosi J. Fetal growth screening by fundal height measurement. Best Pract Res Clin Obstet Gynaecol. 2009;23(6):809–18. https://doi.org/10.1016/j.bpobgyn.2009.09.004

  6. Papageorghiou AT, Ohuma EO, Altman DG, Todros T, Cheikh Ismail L, Lambert A, et al. International standards for fetal growth based on serial ultrasound measurements: the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project. Lancet. 2014;384(9946):869–79. https://doi.org/10.1016/S0140-6736(14)61490-2

  7. Gelbaya TA, Nardo LG. Customised fetal growth chart: a systematic review. J Obstet Gynaecol. 2005;25(5):445–50. https://doi.org/10.1080/01443610500160444

  8. Kiserud T, Johnsen SL. Biometric assessment. Best Pract Res Clin Obstet Gynaecol. 2009;23(6):819–31. https://doi.org/10.1016/j.bpobgyn.2009.06.007

  9. Visser GH, Eilers PH, Elferink-Stinkens PM, Merkus HM, Wit JM. New Dutch reference curves for birthweight by gestational age. Early Hum Dev. 2009;85(12):737–44. https://doi.org/10.1016/j.earlhumdev.2009.09.008

  10. Gardosi J, Francis A. A customized standard to assess fetal growth in a US population. Am J Obstet Gynecol. 2009;201(1):25e1–7. DOI: 10.1016/j.ajog.2009.04.035

  11. Miller J, Turan S, Baschat AA. Fetal growth restriction. Semin Perinatol. 2008;32:274–80. https://doi.org/10.1053/j.semperi.2008.04.010

  12. Mikolajczyk RT, Zhang J, Betran AP, Souza JP, Mori R, Gülmezoglu AM, et al. A global reference for fetal-weight and birthweight percentiles. Lancet. 2011;377(9780):1855–61. https://doi.org/10.1016/S0140-6736(11)60364-4

  13. Hadlock FP, Harrist RB, Martinez-Poyer J. In utero analysis of fetal growth: a sonographic weight standard. Radiology. 1991;181(1):129–33. https://doi.org/10.1148/radiology.181.1.1887021

  14. Gardosi J, Mongelli M, Wilcox M, Chang A. An adjustable fetal weight standard. Ultrasound Obstet Gynecol. 1995;6(3):168–74. https://doi.org/10.1046/j.1469-0705.1995.06030168.x

  15. Ersdal HL, Mduma E, Svensen E, Perlman J. Birth asphyxia: a major cause of early neonatal mortality in a Tanzanian rural hospital. Pediatrics. 2012;129(5):e1238–43. https://doi.org/10.1542/peds.2011-3134

Published
2017-01-25
How to Cite
1.
Fattah AN, Pratiwi KN, Susilo SA, Berguna JS, Irwinda R, Wibowo N, Santoso BI, Zhang J. Indonesian local fetal-weight standard: a better predictive ability for low Apgar score of SGA neonates. Med J Indones [Internet]. 2017Jan.25 [cited 2019Nov.22];25(4):228-33. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/1301
Section
Clinical Research