Lateral facial profile of β-thalassemia major in Javanese children: a photogrammetric analysis

  • Wulan Geraldine Parengkuan Pediatric Dentistry Specialist Program, Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia
  • Sri Kuswandari Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia https://orcid.org/0000-0002-7474-6468
  • Indah Titien Soeprihati Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia
DOI: https://doi.org/10.13181/mji.oa.236834
Keywords: beta-thalassemia, facial bones, photogrammetry
Abstract viewed: 103 times
PDF downloaded: 72 times
HTML downloaded: 28 times
EPUB downloaded: 30 times

Abstract

BACKGROUND Impairment of globin chain synthesis in patients with β-thalassemia major causes ineffective erythropoiesis. This condition triggers bone marrow hyperplasia and can lead to craniofacial bone abnormalities. This study aimed to evaluate the lateral facial profile of β-thalassemia major, identify any differences when compared with a control group of similar age and ethnicity, and reveal the facial profile of β-thalassemia major in Javanese children.

METHODS This cross-sectional study included 35 β-thalassemia major children aged 7–15 years. They were divided into 3 groups based on their age. Lateral facial photogrammetry was taken by measuring the forehead protrusion and nasolabial angle. Data were then mapped to the normal group of children in the same age group and descriptively analyzed using SPSS software.

RESULTS The 1 and 2 SD group had a higher prevalence of β-thalassemia major in children aged 7–9 years for both sexes. The older age group had a closer mean value to those of children without thalassemia.

CONCLUSIONS The forehead and maxillary profile of Javanese β-thalassemia major children tended to be protrusive, especially in the 7–9 years age group, while the older age groups had closer mean values to those of children without thalassemia.

References

  1. Hattab FN. Thalassemia major and related dentomaxillofacial complications: clinical and radiographic overview with reference to dental care. Int J Exp Dent Sci. 2017;6(2):95-104. https://doi.org/10.5005/jp-journals-10029-1163

  2. Ministry of Health of the Republic of Indonesia. [Indonesia health profile 2019]. Jakarta: Ministry of Health of the Republic of Indonesia; 2020. Indonesian.

  3. Rajajee KT, Jampanapalli SR, Govada J, Erugula SR, Sudheer KA, Krishna MM, et al. Prevalence of dental caries, oral hygiene status, malocclusion status and dental treatment needs in thalassemic children - a cross sectional study. Sch Acad J Biosci. 2017;5(1):41-6.

  4. Toman HA, Hassan R, Hassan R, Nasir A. Craniofacial deformities in transfusion-dependent thalassemia patients in Malaysia: prevalence and effect of treatment. Southeast Asian J Trop Med Public Health. 2011;42(5):1233-40.

  5. Sharma S, Basalingappa S, Revankar AV, Patil AK. Orthodontic extraoral photography: comparative subjective analysis of five digital single lens reflex cameras. APOS Trends Orthod. 2013;3(5):131-6. https://doi.org/10.4103/2321-1407.119094

  6. Moshkelgosha V, Fathinejad S, Pakizeh Z, Shamsa M, Golkari A. Photographic facial soft tissue analysis by means of linear and angular measurements in an adolescent Persian population. Open Dent J. 2015;9:346-56. https://doi.org/10.2174/1874210601509010346

  7. Lindhe J, Bressan E, Cecchinato D, Corrá E, Toia M, Liljenberg B. Bone tissue in different parts of the edentulous maxilla and mandible. Clin Oral Implants Res. 2013;24(4):372-7. https://doi.org/10.1111/clr.12064

  8. Galanello R, Origa R. Beta-thalassemia. Orphanet J Rare Dis. 2010;5:11. https://doi.org/10.1186/1750-1172-5-11

  9. Adamopoulos SG, Petrocheilou GM. Skeletal radiological findings in thalassemia major. J Res Pract Musculoskeletal Syst. 2020;4(3):76-85. https://doi.org/10.22540/JRPMS-04-076

  10. Sharma P, Arora A, Valiathan A. Age changes of jaws and soft tissue profile. Sci World J. 2014;2014:301501. https://doi.org/10.1155/2014/301501

  11. Leung CS, Yang Y, Wong RW, Hägg U, Lo J, McGrath C. Angular photogrammetric analysis of the soft tissue profile in 12-year-old southern Chinese. Head Face Med. 2014;10:56. https://doi.org/10.1186/s13005-014-0056-3

  12. Scutellari PN, Orzincolo C, Andraghetti D, Gamberini MR. [Anomalies of the masticatory apparatus in beta-thalassemia. The present status after transfusion and iron-chelating therapy]. Radiol Med. 1994;87(4):389-96. Italian.

Published
2023-12-22
How to Cite
1.
Parengkuan WG, Kuswandari S, Soeprihati IT. Lateral facial profile of β-thalassemia major in Javanese children: a photogrammetric analysis. Med J Indones [Internet]. 2023Dec.22 [cited 2024May22];32(3):173-6. Available from: http://mji.ui.ac.id/journal/index.php/mji/article/view/6834
Issue
Vol. 32 No. 3 (2023): September
Section
Clinical Research

Copyright (c) 2023 Wulan Geraldine Parengkuan, Sri Kuswandari, Indah Titien Soeprihati

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with Medical Journal of Indonesia agree to the following terms:

  1. Authors retain copyright and grant Medical Journal of Indonesia right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial License that allows others to remix, adapt, build upon the work non-commercially with an acknowledgment of the work’s authorship and initial publication in Medical Journal of Indonesia.
  2. Authors are permitted to copy and redistribute the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Medical Journal of Indonesia.